Liverpool, Manchester City, Manchester United and Tottenham Hotspur have all found out their opponents in Europe's premier club competition.
Manchester City have the easiest of rides of the quartet, being pitched against Lyon, Shakhtar Donetsk and Hoffenheim.
Tottenham can look forward to encounters with Barcelona and Inter Milan, Manchester United will play against Valencia and Juventus, while Liverpool will meet Napoli and Paris Saint-Germain.
Here is the full schedule and all the kick-off times for this season's competition...
Matchday 1: 18-19 September
September 18
- Club Brugge vs Borussia Dortmund (8PM)
- AS Monaco vs Atletico Madrid (8PM)
- Barcelona vs PSV Eindhoven (5.55PM)
- Inter Milan vs Tottenham Hotspur (5.55PM)
- Liverpool vs Paris Saint-Germain (8PM)
- Red Star Belgrade vs Napoli (8PM)
- Galatasaray vs Lokomotiv Moscow (8PM)
- Schalke vs Porto (8PM)
September 19
- Ajax vs AEK Athens (5:55PM)
- Benfica vs Bayern Munich (8PM)
- Shakhtar Donetsk vs Hoffenheim (5:55PM)
- Manchester City vs Lyon (8PM)
- Real Madrid vs AS Roma (8PM)
- Viktoria Plzen vs CSKA Moscow (8PM)
- Young Boys vs Manchester United (8PM)
- Valencia vs Juventus (8PM)
Matchday 2: 2-3 October
October 2
- Bayern Munich vs Ajax (8PM)
- AEK Athens vs Benfica (8PM)
- Hoffenheim vs Manchester City (5:55PM)
- Lyon vs Shakhtar Donetsk (8PM)
- CSKA Moscow vs Real Madrid (8PM)
- AS Roma vs Viktoria Plzen (8PM)
- Juventus vs Young Boys (5:55PM)
- Manchester United vs Valencia (8PM)
October 3
- Atletico Madrid vs Club Brugge (8PM)
- Borussia Dortmund vs AS Monaco (8PM)
- Tottenham Hotspur vs Barcelona (8PM)
- PSV Eindhoven vs Inter Milan (8PM)
- Paris Saint-Germain vs Red Star Belgrade (5.55PM)
- Napoli vs Liverpool (8pm)
- Lokomotiv Moscow vs Schalke (5.55PM)
- Porto vs Galatasaray (8PM)
Matchday 3: 23-24 October
October 23
- AEK Athens vs Bayern Munich (5:55PM)
- Ajax vs Benfica (8PM)
- Hoffenheim vs Lyon (8PM)
- Shakhtar Donetsk vs Manchester City (8PM)
- AS Roma vs CSKA Moscow (8PM)
- Real Madrid vs Viktoria Plzen (8PM)
- Young Boys vs Valencia (5:55PM)
- Manchester United vs Juventus (8PM)
October 24
- Club Brugge vs AS Monaco (5.55PM)
- Borussia Dortmund vs Atletico Madrid (8PM)
- PSV Eindhoven vs Tottenham Hotspur (5.55PM)
- Barcelona vs Inter Milan (8PM)
- Paris Saint-Germain vs Napoli (8PM)
- Liverpool vs Red Star Belgrade (8PM)
- Lokomotiv Moscow vs Porto (8PM)
- Galatasaray vs Schalke (8PM)
Matchday 4: 6-7 November
November 6
- AS Monaco vs Club Brugge (5:55PM)
- Atletico Madrid vs Borussia Dortmund (8PM)
- Tottenham Hotspur vs PSV Eindhoven (8PM)
- Inter Milan vs Barcelona (8PM)
- Red Star Belgrade vs Liverpool (5:55PM)
- Napoli vs Paris Saint-Germain (8PM)
- Porto vs Lokomotiv Moscow (8PM)
- Schalke vs Galatasaray (8PM)
November 7
- Bayern Munich vs AEK Athens (8PM)
- Benfica vs Ajax (8PM)
- Lyon vs Hoffenheim (8PM)
- Manchester City vs Shakhtar Donetsk (8PM)
- CSKA Moscow vs AS Roma (5:55PM)
- Viktoria Plzen vs Real Madrid (8PM)
- Valencia vs Young Boys (5:55PM)
- Juventus vs Manchester United (8PM)
Matchday 5: 27-28 November
November 27
- AEK Athens vs Ajax (5:55PM)
- Bayern Munich vs Benfica (8PM)
- Hoffenheim vs Shakhtar Donetsk (8PM)
- Lyon vs Manchester City (8PM)
- CSKA Moscow vs Viktoria Plzen (5:55PM)
- AS Roma vs Real Madrid (8PM)
- Manchester United vs Young Boys (8PM)
- Juventus vs Valencia (8PM)
November 28
- Atletico Madrid vs AS Monaco (5:55PM)
- Borussia Dortmund vs Club Brugge (8PM)
- PSV Eindhoven vs Barcelona (8PM)
- Tottenham Hotspur vs Inter Milan (8PM)
- Paris Saint-Germain vs Liverpool (8PM)
- Napoli vs Red Star Belgrade (8PM)
- Lokomotiv Moscow vs Galatasaray (5:55PM)
- Porto vs Schalke (8PM)
Matchday 6: 11-12 December
December 11
- Club Brugge vs Atletico Madrid (8PM)
- AS Monaco vs Borussia Dortmund (8PM)
- Barcelona vs Tottenham Hotspur (8PM)
- Inter Milan vs PSV Eindhoven (8PM)
- Liverpool vs Napoli (8PM)
- Red Star Belgrade vs Paris Saint-Germain (8PM)
- Galatasaray vs Porto (5:55PM)
- Schalke vs Lokomotiv Moscow (5:55PM)
December 12
- Ajax vs Bayern Munich (8PM)
- Benfica vs AEK Athens (8PM)
- Shakhtar Donetsk vs Lyon (8PM)
- Manchester City vs Hoffenheim (8PM)
- Real Madrid vs CSKA Moscow (5:55PM)
- Viktoria Plzen vs AS Roma (5:55PM)
- Young Boys vs Juventus (8PM)
- Valencia vs Manchester United (8PM)
